Fully Alive: Unlocking the secrets to your healthier, happier, longer life - Zach Gurick | Jesse Levey And Hunter Ziesing | AI-Empowered Medicine

 

Medical tests and treatments are dreaded by many because they often break the bank. But thanks to AI-empowered medicine, this unfortunate reality may be finally changed for the better. Zach Gurick is joined by Hunter Ziesing and Jesse Levy of Longevity Health, who harness the power of AI to close the gap between cutting-edge science and everyday life. They explain how they unpack a patient’s why to provide them with customized longevity plans tailored to their specific biological needs. Hunter and Jesse also explain how to separate hype from science, the importance of focusing on data-driven disease prevention, and their mission to help one billion people live up to a hundred years old.

The information presented in Fully Alive is for educational and informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment and before making changes to your health regimen. Guests’ opinions are their own and do not necessarily reflect those of the podcast host, production team, or sponsors.

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Future Of AI-Empowered Medicine With Jesse Levey And Hunter Ziesing

Welcome back to the show, where we are unlocking the secrets to your healthier, happier, and longer life. We’re diving deep into the future of personalized health and longevity with two leaders who are on a mission to help people extend not just their lifespan, but their health span. Our guests are Hunter Ziesing and Jesse Levy from Longevity Health, a platform that’s designed to create a personalized blueprint for optimal aging, performance, and long-term vitality.

Hunter’s journey into longevity is born out of a personal experience and a vision to close the gap between cutting-edge science and everyday life. Jesse brings a practical lens to the conversation, emphasizing that longevity isn’t about chasing every biohack, but doing the basics incredibly well, consistently, and intentionally.

Together, they’ve built a system that combines advanced biomarkers, lifestyle design, and evidence-based interventions to help people take charge of their future health. In this episode, we’ll explore what really moves the needle when it comes to longevity, how to separate hype from science, and why mindset, clarity, and simplicity matter just as much as technology and medicine. Get ready to learn how you can craft your own roadmap to living fully alive with Hunter and Jesse from Longevity Health.

 

Fully Alive: Unlocking the secrets to your healthier, happier, longer life - Zach Gurick | Jesse Levey And Hunter Ziesing | AI-Empowered Medicine

 

Jesse and Hunter, you guys, thank you so much for joining us. Ever since learning about your company and getting to talk with you a couple of weeks ago, I’ve been really excited to have this conversation to hear about the amazing things that you’re putting together, the work that you’re doing to really scale this, and to make it accessible for millions of people. Hopefully, to really shift things in the future of healthcare and medicine, and our approach to it. Thanks for joining us. I’m excited to dive into this conversation.

Great to be here.

How Jesse And Hunter Started Longevity Health

I’d always love to start just at the beginning, like what really was the impetus that caused you guys to dive into the space and really create this company? How did you end up where you are?

I have a family history of heart disease. Both of my grandfathers had heart attacks before the age of 50. That just had me really motivated to be healthy my whole life. I ran three marathons, I did CrossFit for ten years, I tried every diet out there, paleo, vegan, pegan, juice cleanse, like you name it, I tried it. It was about 3 or 4 years ago, I found the longevity space, and it just like really spoke to me as something I wanted to do in my own life.

I ran into three real problems. The first problem was that the people I was listening to and reading about the luminaries in space were all saying different things. It was very confusing. It was hard to sort through that to figure out what was relevant. The second problem I found is that, as I started searching around for trusted advice, I found a bunch of companies trying to sell me something.

Supplements, blood tests, CGMs, wearables, peptides, hormones. All of which probably had some benefit, but it was hard to trust the advice because everybody was basically trying to make a buck. The third problem I found is that I went to my primary care physician, and she was just really dismissive. I found that the healthcare system in general was really lacking in its adoption of longevity medicine or what Peter Attia calls medicine 3.0, a much more focused approach on prevention, aggressive screening, and trying to make sure that we don’t get sick, versus treating us once we are sick.

I couldn’t find what I was looking for. I couldn’t find the support. I couldn’t find a concierge practice that I was ready to spend money on, but I couldn’t find much. I decided to start it myself and launch longevity health. Our vision is to take a longevity-focused concierge practice, which traditionally is like $100,000 or more, and make that accessible to the masses for as low as $10 a month through technology and AI.

That’s the vision of the company. We have a three-phased approach to do that. Phase one is to replicate the $100,000 a year clinic for $10,000. That’s life. We’ve been live for almost two years. That’s a cross between an executive physical focused on longevity and a concierge medical practice focused on longevity. We do a bunch of testing and screening, and diagnostics. We give you a team.

We call it a personal longevity board. It’s like a board of directors for your health, and they help you manage your care. Phase two, which we’re transitioning into right now, is an AI doctor, an AI agent that talks to you about your care, asks you a bunch of questions, but also has a doctor in the loop. That allows you to trust that the AI agent is going to make mistakes and have a doctor to actually execute on any of the recommendations.

We went from $100,000 initially, and our first product was $10,000. This next product is a $1000. Eventually, as the regulation allows the doctor in the loop to fade to the background and the agent takes over more, and once we can get the agent really to be able to practice more medicine as the regulation allows, that becomes $100 or $10 a month. We went from a $100,000 down to $10,000. Now we’re at $1,000, and eventually we’ll be a $100. That’s the vision. I want to get a billion people to live to be a hundred in good health.

That’s an amazing vision. I love that you can clarify it so clearly like that, too, a billion people to live to a hundred in good health for $10 a month.

That’s pretty amazing.

You’re taking an approach that makes sense. Tell me a little bit. I know Hunter’s on the call too. How did you team up with Hunter? Hunter, you have your own story of what led you into this space as well. I’d love to just capture that.

I’ll take that one. I spent twenty years on Wall Street. I’ve been an athlete since my early twenties. I was a professional bike racer off and on. At least I thought I was. Sadly, I lost my dad and five of my friends to cancer or other infectious diseases that could have been prevented. I had done well on Wall Street. I took a turn and I started a foundation to help nonprofits, largely renowned cancer centers around the Livestrong Foundation, on the research side.

I did that for 12 or 15 years. I’ve always been a data junkie. I just really started hacking around with health data, trying to merge health records with wearable data and building a company to help consumers use that data for prevention. I quickly learned, as I teamed up with Jesse, that you need a lot more data than just a single blood test or some wearable data or your HIPAA records, which are your health records, which are very dark and old, hard to read, and historical data.

You need a lot more data than a single blood test or your health records to vastly improve your health and extend your life.

You really need more functional testing data than you’re seeing, in addition to blood tests such as dexascans, which are fairly inexpensive, and Jesse can get into Sleep tracking, stress management, emotional management, to gut biome tests. These are all becoming readily available and at a cheaper price for consumers. That’s something we’re trying to do is really individualize those tests to specific consumers and use that data to get ahead of infectious diseases before they hit you later in life.

That was my big wake-up call. Jesse knew through, Jesse had been in the FinTech business for many years. He was the president of Credit Sesame, and we knew each other. I came over to join Jesse to focus on the partnerships and marketing side of the business. Jesse’s built out this incredible clinical model. Long answer to your question.

That’s great. I love how both of you have significant expertise and experience, and now you’re applying that in this longevity space in a model that is really very functional and can really work for people. Thank you for making that shift, and you’re going to change a lot of people’s lives.

Jesse can address it, too. One of the things that I noticed back when I was losing friends or watching people who take incredibly bad care of themselves, it’s not just money. They lack the tools, they lack the motivation. They know they have a problem. They’re going to run into problems, but they don’t develop a plan.

 

Fully Alive: Unlocking the secrets to your healthier, happier, longer life - Zach Gurick | Jesse Levey And Hunter Ziesing | AI-Empowered Medicine

 

There’s nothing out there to curate all this information into a plan, let alone make it affordable. I know a lot has to change. Reimbursement needs to change for all these wonderful tests that are being done because people don’t want to pay for them. That’s changing. Also, people are just confused by this barrage of data. They’re going into ChatGPT, they’re loading their stuff into Chat, and they’re like, “Tell them what to do.”

They don’t really know how to put all this longitudinal data together. I think that’s what I love about what Jesse’s done, and maybe he should address a little about what we’ve done from the clinic. We started as a clinic. We’re just not a data aggregation or a testing company. We’re really using clinical science to change people’s direction. I’ll let Jesse take it from here on that.

That’s great. Jesse, I love how you start off with your own journey of identifying these three problems. I think myself and probably a lot of us tuning in can attest to those, running into those same barriers, that there are differences of opinions or confusing messages like, “Take this supplement.” Somebody else says, “No, don’t take that supplement. We should all be taking this.”

Somebody else says, “No, we shouldn’t.” What biohacks to do and which ones are most effective, and all of those things like those competing messages. Everybody, like you said, is selling a product, or not everybody, but a lot of people have a product to sell. Our traditional physicians are not trained in what you referred to, Jesse, as medicine 3.0, like that predictive preventative model that is coming, that’s here now, and is coming more of a functional approach, getting at the root cause.

Starting With Your Why, Not With Your How And What

Our primary care physicians are often dismissive. I really can relate to those three. I love how you started off by identifying those challenges. Can you walk us through that? Let’s just start with the $10,000 concierge model at this clinic. What does that look like? What tests are you doing? How are we addressing those three challenges?

What I want to do is give people the tools to do this themselves. I can include some of the things we do in the clinic, because I think that there’s this misconception that this has to be really expensive. It’s not free, but the majority of things that you can do to extend your lifespan and your health span actually are very low-cost. We do it in the clinic, but everyone has the tools to do this themselves.

The majority of things you can do to extend your lifespan and health are actually low-cost. Everyone has the tools to do this themselves.

The way that we describe the process is you really want to start with why. Why do you even want to live longer and healthier? For me, I want to ski in my 80s. I want to hike in my 90s. I want to be alive at 102 to meet my great-grandchildren, if I have any. I want to be active at 102. I want to be in good health. You start with why, and then you focus on how. What happens is that most people jump to what? What should I do?

What supplements should I take? What exercise should I do? What drugs should I try? What medication all sorts of things, versus like, how are you going to actually achieve your goals? If I want to ski in my 80s, I probably need a VO2 max when I’m 80 of about 30, let’s say. If we assume that I’m going to have a decline in my fitness, 45 right now, over the next 35 years, then I probably need a VO2 max today somewhere around 55 mid-fifties.

When I first started on this journey, I told you I ran three marathons. I was very active. My VO2 max was 39, which was slightly above average, nowhere near where it needed to be, and certainly not elite. I shifted my training to focus on that and got it to 51. I’m not at 55 yet, but I’m on the path. That’s a little bit more about the how. How do I achieve my goal as well? I need a really high VO2 max. I also need to avoid getting a chronic disease.

The four diseases most likely to kill you that Peter G calls the four horsemen, heart disease, diabetes, dementia, and cancer, and I need a specific strategy to prevent each of them, which I have. Because I have a family history of heart disease, I may be more aggressive there than somebody else. The first thing I tell people is, “You need to have a plan.” The plan isn’t like, “I’m just going to do these, take these supplements, or exercise.”

It has to be a strategy that’s aligned with your goals, your biology, your lifestyle. Any information we get from biomarkers, etc. That then drives into the what. What specifically should you be doing? For me, like trying to improve my VO2 max, I’m doing intervals to do that. I’ve got a whole protocol of Norwegian 4 by 4 to improve my VO2 max. That’s because I had a very specific strategy based on my goals and what we found in the testing.

I love that. Thanks for breaking that down for us, too. I love just how you’ve made things very clear and simple. I think even like on your website, I love the quote that you put on there. It’s really about doing the basics really well. I’m not quoting it exactly, but it’s about doing the basics incredibly, incredibly well.

As you said, these are things that all of us can do, but setting it up with that starting in that framework, starting with why, and then the how, and then the what, and most of the things that will answer these problems are those day in and day out habits that our lifestyle choices that we can make without spending a whole lot of money. Anybody can go run intervals. If you’re assuming you’re able to run a little bit, start small.

Four Recommended Tests Most People Should Get

I love how you said like skiing your 80s, hiking your 90s, and be alive at 102 and meet your great grandkids. That’s pretty fun. Walk us through that with the AI agent version. Maybe just before we dive into that, I’d love to hear about some of the other tests that you’re utilizing to help people create that strategy or to measure the biomarkers and things like that.

I like to say you can do this on any budget, but there are four tests that we generally recommend most people should get. First is excessive blood work. Probably had some blood work, you can get that included with your insurance. It’s pretty basic. If you can afford to do more extensive blood work, we recommend that. There are a bunch of companies that do that. We do it in our program as well.

The second is a DEXA scan. Dexascan I find is usually one of the most impactful things. Usually, people have already had some blood work, but often they’ve never had a DexaScan. A DEXA scan is a low-dose X-ray. It has very low radiation. It’s telling me it’s like eating four bananas. You shouldn’t really worry about that, but it was going to tell you four pieces of information. It’s going to tell you your muscle mass, your bone density, your visceral fat, and your total body fat.

There’s some really important information here which one of the things that frustrates me is that people go into the doctor and the doctor says, “You need to lose 15 pounds.” You have no idea. They’re probably using some outdated BMI calculation. Until you actually do a DEXA and you find out how much visceral fat someone has and how much muscle mass they have. You really don’t know if they need to lose weight or not.

Visceral fat is the fat that’s around your organs. It’s the fat that is most dangerous, and it is highly specific to the individual. You could take two men who are both 25% body fat. One of them might have one pound of visceral fat, and the other might have three pounds. Even though they look the same on the outside, on the inside, there’s a different biology that leads one to hold more visceral fat than the other.

If you have three pounds of visceral fat, one of the top things that you should do is lose weight. You probably do need to lose fat. If you have one pound, you might need to lose weight, but you might also need to do other things, like build muscle and improve your bone density. That’s one really important piece of information. Another one that I just want to plug is bone density. Bone density, the standard recommendation for women is to get their bone density tested at 65, and for men, is to get it tested at 70 is almost certainly too late, especially for women.

After menopause, it becomes much harder to improve your bone density. My wife is in the program. I’m in the program as well. We tested her bone density, and her bone density was low. She was in her early forties, and she could still do something about it. She has a very specific and structured program to improve her bone density. That’s just an example of how my program is focused on VO2 max.

Her program is focused on bone density, and she has different exercises, a different diet, and different supplements than I do. This has a plan with high specificity, and the testing helps you get there. DEXA scan is two. VO2 max is three, which measures your cardio-respiratory fitness. It’s also going to tell you your zone two threshold. That’s really helpful in evaluating where you should focus.

The third one that we recommend is a continuous glucose monitor. I’m not a big believer that everybody needs to flatten their glucose curve, and we need to all just try to manage the amount of glucose in our bloodstream, but most Americans do. 93% of Americans have one of the signs of insulin resistance. Because of that, most people, that as a big opportunity. It’s one of the things for them to focus on.

You’re going to get some information in your blood work that’s going to help you get a sense of are you’re insulin resistant. The CGM gives you more information. We do recommend that for everyone. I will say, though, that if you’re generally healthy, you don’t have any signs of insulin resistance, you’re very insulin sensitive. We generally do not recommend wearing a CGM all the time or monitoring for that all the time, or trying to keep your glucose really low all the time.

Generally, there’s probably going to be other things for you to focus on, but the testing helps us to figure out and helps you to figure out what’s most important for you to spend your time. This is where having the plan with a high degree of specificity becomes so important. What I find in the longevity space is that this is what most people are missing. This is what I was doing too. It’s like people are doing things randomly, intermittent fasting, supplements, hyperbaric oxygen chamber, peptides, whatever it is.

You heard it on social media. Huberman talked about it on his podcast. A friend told you to try some stem cell therapy, and so you go and do it, versus actually doing the testing and figuring out what’s going to be most impactful for you. It’s not that those other things are bad. It’s just that they’re not the place where you should be spending your time and money first. Unless you’re like Brian Johnson, who’s spending $2 million a year on his longevity and trying to do all of the above. Most people have a limited capacity for focus on this stuff. Making sure that your time and money are most focused is really critical, and the testing helps you do that.

The DEXA scan test, for example, is, like you said, relatively inexpensive. Most people probably aren’t doing that. Most doctors aren’t recommending you go do this as part of your annual checkup. It’s a couple $100 dollars for most people. I’ve heard it as low as $40.

It’s usually like $50 to $100. You don’t need a diagnostic DEXA at an imaging center. You need a DEXA scan at one of these other facilities that offer direct-to-consumer. You don’t need a doctor to order it. In some states, in most states, you don’t need a doctor to order it. It’s usually $50 to $100.

Putting Together A Personal Longevity Board

Most budgets could swing that, and then you get all that critical information and data to help formulate the plan. I love that. In the $10,000 model that you have, you’re doing this, getting the baselines, structuring the plan, then wrapping it around with longevity experts, longevity-focused physicians. People who are experts, including nutritionalists and other coaches.

In our program, we do all the testing I mentioned, plus additional testing, and then we actually repeat it. My wife is trying to improve her bone density. She’s going to be on a program for three months. We’re going to repeat the DEXA scan and see if she’s improved. I’m trying to improve my VO2 max. I do the program. Six months later, I retest to see how it has improved. Same with blood work. We’re repeating the testing.

We put together a team. We call it a personal longevity board. It’s like a board of directors for your health. As you mentioned, a cross-functional team that includes a longevity-focused physician, an exercise physiologist, a nutritionist, and a strength and conditioning coach. That’s your team. They actually meet together to review your case. Every Tuesday morning, we actually met this morning, we go through any patient that has had an update, either new testing or some new consult or something, and we review the new information and revise their program accordingly, and send them these recommendations.

They can meet with the team as much as they want. They can have messaging, all of that back and forth. We want to make sure they have real access to the team, but we also want to take off the burden from the patient to the team. Sometimes we do some testing and we find things that need follow-up. They may be concerning, but we don’t know yet. One of the things we tell our patients is, “We don’t know that this is something to be concerned about or not.

You don’t need to be concerned about it because we are concerned about it. We’re going to take that burden on and we’re going to follow up, and we have a clear plan for all of the things that you can do,” versus what often happens in the healthcare system, which is that I have a family member where this is the case, where you go in. You get some routine testing, something is anomalous, and the doctor’s like, “I don’t know. Maybe try this. We’ll try this next test.”

You do another test, and it’s inconclusive, and you do another test, and that leads to another follow up and you’re the one who has to own it and drive it and follow up on it because it’s all these different specialists that are not coordinating with each other. It may turn out to be nothing, or I have friends where it turns out to be something, and it took nine months to get like a cancer diagnosis. Meanwhile, that sucker is growing inside of you. You’re losing time. We take on that burden and coordinate and move quickly.

We have a medical concierge who will actually go out and find the place where we can get the follow-up testing. Sometimes it’s not like this place down the road is not the place you want to go because it’s going to take six weeks to get the testing, versus if you drive twenty minutes, we can get you in and six things. We’re always doing that. By the way, I just want to say, like most people don’t find things concerning, but the team can help to really manage that if we do.

Just to be clear, this program that we have it’s called the billionaire bundle. It’s not for billionaires, but it’s what a billionaire might get. It does cost just under $11,000 a year. It’s all virtual. We either test your home or we send you out to testing partners. All the tests go into an account, a private HIPAA-compliant account, where our medical team can look at them.

Bricks and mortar of clinics range from $15,000 to $30,000 a year, or you can go to Peter Atias Clinic, which I think costs $200,000 a year. There’s actually a waiting list for Peter. Jesse, maybe you can explain how, because I know Zach wants to know how we can make this more affordable using AI, and talk a little bit about the transition to AI. Everybody’s all enamored with AI, but we both know it’s taking a little bit longer, and we can even demo some of this for Zach if you want.

Making Tests More Affordable And Accessible Through AI

The biggest challenge in the longevity space, I mean, this will be based on those three problems that I mentioned, is designing your own custom plan, taking all the information, customizing it to your own biology, and then developing the plan based on you and where you’re at. That is something that we do in the clinic with a team, but actually doesn’t have to be delivered via humans because AI is really well equipped to do that.

It’s only going to get better. We have built an AI agent. We call it Longevity, Jesse. It’s trained on a lot of my content, but also on what we do in the clinic and the process that we run, and the clinical expertise that we have, and the results that we’ve delivered to our patients. It runs through all this information. It takes information from you, designs a plan, and then you can actually in through our HIPAA-compliant EHR upload any tests that you do.

It will probably recommend for most people, but ends up recommending a couple of tests. It might say get blood work in a DEXA scan. You go do that. Again, it’s not that expensive. You upload it into the system, and then the AI agent can continue, can review it, and can see now you have all these tests done. What’s going to be the next thing for you? Every time you call it, it updates your plan. In the version of the program that we have, I’m launching right now, a doctor then reviews the plan to make sure it’s accurate.

Also follows up on any execution of anything that needs to be done, like ordering lab work or referrals or medication, or whatnot. That’s how we get the cost way down. Eventually, some people think I’m crazy. I believe that AI agents will be licensed to practice medicine. It’s not going to be tomorrow, probably not next year, but on some time scale, we will see AI agents, maybe they won’t be doing surgeries, but they will be doing consults and helping you figure out what’s right for you, and even prescribing medication and ordering lab work, etc.

 

Fully Alive: Unlocking the secrets to your healthier, happier, longer life - Zach Gurick | Jesse Levey And Hunter Ziesing | AI-Empowered Medicine

 

Once that’s the case, we can remove the doctor from the loop, and the price can be as low as $10 a month. You still have some cost for the testing, but the cost of testing is coming way down. I believe that from the $10 a month, a $100 a year, plus a couple of hundred dollars in testing. You can have 95% of what we’re doing in the clinic right now for almost $11,000. That’s really the promise. That’s how we get to a billion people. That’s why I’m doing this. That’s what I’m really excited to work on and to talk to you guys about today.

You want to hear it, Zach?

Keeping Your Clinical Data Safe With Longevity Jesse

Sure. I actually got to have a phone call with Longevity Jesse, and then he texted me a plan while I was on the phone after I answered a few questions in about 7 or 8 minutes. Now I have a plan based on just my answers to those questions.

It only takes 30 seconds. My plan’s a little more comprehensive than yours. I’m somewhere between the full AI, longevity Jesse, and the full billionaire Bundle clinic. I’ve done a number of tests. They’re already on the server. I’m just going to Longevity Jesse and just ask a quick question. I’ll put it on speaker. “This is Jesse from Longevity Health. How have things been going?”

“Great. I just got back from Aspen. I felt really good at altitude. I’m actually doing a demo call for a podcast. Could you just quickly share with the audience my blood test results and what you recommended for me from my last comprehensive blood work?” “I’m glad to hear you’re feeling good after your time in Aspen. Let’s dive into your blood test results and recommendations. From your last comprehensive blood work, we noticed a few things.

One, asterisk, asterisk, nocturnal hypoglycemia and renal stress. Your blood test showed significant nighttime glucose dips going as low as 39 milligrams.” Anyway, you get the idea. I can ask questions about my DEXA scan, my VO2 max test, and things to improve. It’s getting better and better. I can call it anytime it remembers my conversations.

I wasn’t asked, and I was a little bit concerned about how I was feeling at altitude. I just called up Longevity Jesse and asked her a question, and she gave me some suggestions for how to even do my intervals at altitude. That’s the future of medicine, and it’s really cool. Importantly, right now there’s going to be a human in the loop.

AI is super cool, but consumers aren’t fully ready for the driverless doctor. AI is not fully ready. It makes mistakes. It hallucinates. It needs a human check. From a regulatory standpoint, as Jesse mentioned earlier, it’s just not ready for prime time, but it’s coming faster. I think it’s coming faster than people think. What I love about this is that all my stuff is sitting on that server. It’s highly secure. It’ll be there for the rest of my life. As I add testing and do more things, as it becomes more affordable, I’ll just download it into the app, and it’ll follow me. When I went to see my doctor, as I did yesterday, I knew more about my medical history than he did.

You’re taking control into your own hands. You’re not just waiting for your doctor to see you once a year and spend seven minutes with you, but you have this all year round built out every day, whatever you’re working on. That’s amazing.

Hopefully, it’ll get better and better. The check engine light will come on and give me warnings, and make recommendations. It’s a big problem. You go to the doctor every year, and it says, “Zach, lay off of this, lay off of that. Don’t do this. Don’t do that. You do it for a week.” Guess what? You fall back into the new year, new you, February it’s over, and you’re back into the same regimen again.

The goal with this, and this is Jesse’s trillion-dollar view, is that we can use this to affect change and change behavior and get the unhealthy to become healthier. My friends, when they were in their 40s, many of them were overweight and obese and running into all kinds of problems. Every year, they said, “I’m going to do something,” and they didn’t because I don’t think they had the tools or the motivation to do it.

I think we talked about that a little bit before. It’s how you actually get people to change those behaviors and have those kinds of motivators in place, I think, that is really key there too.

I think there are financial incentives that motivate people, but also social incentives.

Behavior change is really hard. What I found this, I found in my FinTech days as well, while it’s hard to change behavior, what you can do is you can change beliefs. If you change beliefs, behavior follows. There are two primary ways that we really change beliefs. Number one is getting the testing and the data to be able to see what you need to do. My wife got the data to see that her bone density was low, and her motivation entirely changed for lifting weights.

If you change beliefs, behavior follows.

She’s lifting weights, she’s eating more protein, she’s doing things to improve her bone density because she saw the data changed her beliefs. The second thing that happens is you have a plan that fits into your lifestyle. An achievable plan. I cannot tell you how many people come to us who are new to exercise. They are just getting started with things, and they want to run before they walk. Literally. It’s like, “I’m going to work out five days a week, whatever.”

I was like, “No. I want you to work out for 30 minutes a week and no more. Ten minutes, three times a week. That’s what we’re going to start.” Now you have a plan that you actually feel like you could do for the rest of your life. You have more confidence, and now your motivation has changed. That’s where the behavior change comes in is really trying to change beliefs and behavior follows. If you do 30 minutes a week for six weeks, now we’re going to bump that up to 60 minutes. We can incrementally improve things, and it becomes a change in who you see, how you see yourself, which then results in the behavior change over time.

You get those small wins along the way. It makes it easier to keep going.

That’s an exactly an important point. It’s like you get this reinforcement because we retest. My wife saw that her bone density has improved, and she’s even more motivated to stay with the program.

That’s great. I love that. This AI agent version that we have now has been checked by a doctor, Longevity Jesse. You said that’s about $1,000. Is that like an annual fee, or do you pay monthly, or how do you get access to that?

It’s $99 a month. We’re in a private beta right now. We have a very limited number of spots because we want to roll this out slowly. If you’re interested, Jesse@LongevityHealth.me, you can go to our website, LongevityHealth.me. Reach out to me, and you can schedule a consult. We can go over it and talk to anybody about it who’s interested.

They get their tests done as recommended based on those needs. You can funnel all of that data into longevity.

You can upload any tests you’ve already done. If there are additional tests you need, we actually have different tiers of the program. Some, for a higher fee, actually include some of the tests, but at the base level, $99 a month, pay for the test. We’ll help you figure out what’s right. We’ll order it for you. We’ll make sure that it gets incorporated into your plan. The doctor will follow up on it to make sure the AI agent is all accurate, all of that.

I’m curious, you mentioned earlier that Hunter, you also mentioned about AI, it’s coming faster than we think. I believe, and I think maybe through some of our earlier conversations, that it isn’t maybe in Singapore and Israel that AI is actually prescribing medications currently.

I heard they’re testing it. I have not verified. Are you Jesse?

I haven’t seen AI. I know that there are frameworks that are being tested, and I do think it’s coming. It may not be the US that leads the way on this. It could be other countries, Singapore and Israel. I definitely think there are two of the more forward-thinking countries around longevity. I know there’s a ton of stuff going on in both countries.

How Jesse And Hunter Take Care Of Themselves

This could be coming sooner. The $10 a month version could be coming sooner than we imagine, even. That’s super exciting. I’m curious, maybe I would love to hear from both of you guys, because you’re doing this, you’re tracking, you’ve already mentioned some of the things that you’re doing in your own personal lives. I would love for each of you to maybe walk us through, like a day or a week, of how you take care of your health. How do you meet your goals? What does your plan look like? How are you implementing that plan as far as biohack supplements? What are you eating, nutrition, workout, exercise, that thing?

I can give you the short of it from my end, having just gone through the program. I used to ride like a maniac 10 or 12 hours a week, hard VO2, just destroying my body on group rides, which is fun. No weightlifting. I’m super healthy, but when I did the DEXA scan, there was a lot of stuff that came up. I had some visceral fat in some places that I didn’t know about.

My bone density was okay. My VO2 was surprisingly lower than I thought, considering how much I’ve been cycling and riding all these years, and my diet sucked. What I’m doing now is I’m doing more weight training and less hard VO2 interval-type stuff. Although I’d like to get my VO2 up. I think what I got back from it, I just need some more steady zone one and zone two training. I need to make some changes.

I won’t go into details of my blood work, but there were some red flags that came out, which shocked me for my age and my fitness. The weight thing has been a big change for me, as is the diet. I don’t go into the whole thing. I’m still developing it. I know what to do. The next thing I need to do is to follow the plan. Those are some of the changes that I’m making. Sleep, no issues at all for me.

That’s great. I’d love to just pause there because you’re a super healthy person. Most of us think, “You’re cycling 10 or 12 hours a week and doing these crazy long group rides and things like that. You must be super healthy in all these ways,” but then you actually look at the data, and there are some areas of improvement. I think that’s that’s important just to let that sink in for all of us that how important it is to actually have this data to stand on get a baseline.

 

Fully Alive: Unlocking the secrets to your healthier, happier, longer life - Zach Gurick | Jesse Levey And Hunter Ziesing | AI-Empowered Medicine

 

Another one is that my testosterone was low, and it’s not a matter of sex drive, but it’s a matter of energy, and I’ve noticed a little bit more fatigue. I’m in my sixties now, so I’m starting to get on the back end of things to start to deteriorate. That’s something I want to work on, and it’s not just getting injections, like I went to two blood test companies, and they both wanted to sell me testosterone injections. I’ve started a weight program, and I’ll retest in three months and see where that is. I’ll let you know.

If you’re going in the right direction, there.

Anyway, Jesse’s been doing this a lot longer than me and he probably has some great things to share, as well as what some of our patients have gotten from really getting into their data.

I think for me, the thing that there are a few big things that stand out diet and exercise or foundational, but actually what was impactful for me was more specificity, not more rigidity. I actually work out five days a week, but I’m not working out any more than I was before. If anything, I’m working out less. I just have more specificity in terms of the strength training program that I’m doing, the intervals that I’m doing, doing a lot of walking as well, like just really with a high degree of specificity based on my goals.

We adjust the plan as we see how I’ve responded. My diet is actually more flexible than it’s ever been because I try to eat mostly whole foods. I’m not eating junk, but I have this rubric of I track to about 2,500 calories, 150 grams of protein, and 50 grams of fiber. With those three goals, if I hit those three goals, I haven’t had a healthy diet. You cannot eat a lot of junk and still maintain the caloric intake of the protein and the fiber.

I tracked those three things. I’m not overly concerned if it’s 45 grams of fiber. It’s fine. If I have 2,600 calories one day, is fine. Again, the specificity of the goal that works for me. It’s not necessarily the thing that works for everyone, but I also have incredible confidence. I always have this fear about heart disease, and I don’t want to overlook that because I think that people are focused on the things you can do in front of you.

The actions, the what versus like, actually, I have a strategy to prevent heart disease. That includes cardiac imaging, where I’m imaging my heart. I have a target for my lipids. I’m not on any medication, but I have a target. I know where we’re trying to be. If I get out of range, I may start medication. We’ve done this holistic view, both the images of my heart, the lipid profile, the inflammation that I have, and the metabolic health.

I take this holistic view of the things that can cause heart disease to make sure that everything is in a good place. Despite my family history, I don’t have to worry about it because I know heart disease is something that takes 30 to 40 years to develop. As long as I maintain the path I’m on, the chances I get heart disease are very low. I do want to mention sleep as something for me, which was a really important focus.

I have a very strict program around sleep. It’s probably stricter than my program around exercise or diet, because I wake up at night, and this really helps it. It’s a dark room, no devices. I use mouth tape, I have nasal strips, and I’ve seen an ENT to try to improve my breathing. There’s like a whole host of things. Again, Hunter doesn’t have any problems sleeping. My wife doesn’t have any problems sleeping.

We all go deep in different areas, and that’s the place where I chose to go really deep. The other thing for me is like, I’m going to be in bed eight hours a night. I want to do the other things that take me 10 to 15 minutes a night to improve the return, the time that I’m getting in sleeping in bed, and improving the quality of my sleep. That has been a huge focus for me. That has all these other benefits, more energy, more mental focus, which has really improved my life in many ways.

A Few Success Stories At Longevity Health

Good for your brain health. That’s part of your strategy to avoid dementia and those kinds of things. Yeah. That’s great. Maybe in the next few minutes that we have left here, I’d love to just hear a couple of testimonial stories of patients that have gone through some of your, either the billionaire blueprint are utilizing longevity, Jesse, and have had some turnaround stories. Could you share a couple of stories, maybe?

We had a few really impactful stories that I can share. Oftentimes, people come to us with a complaint. There’s something that’s not quite right that the medical system has rejected. In one case, there was a woman who came, and she was just fatigued, and people say, “You’re in your 40s, you’ve got young kids, you’re a working mom.”

That’s natural. While that may be true, you’re still gaslighting somebody’s own lived experience, and you may be missing something if you take that view. We did some real deep analysis, and I always tell people when they come in with something that they’re feeling that the medical system has dismissed because it’s not like super serious, but it is definitely an issue in their life. I cannot guarantee we will find the root cause, but I can guarantee we will go down this path with you, and we will keep digging until we find something or you tell us you don’t want us to dig anymore.

In this case, we found a thyroid issue. She had a thyroid issue. We were able to address that with medication, and things turned around. This then had all these other positive benefits. Improved her sleep. She was able to exercise more. She was eating better. All of these other things actually were very hard to do because of this underlying issue. Once we address that issue, the other things all improve. That’s one example.

There’s another example of somebody who came to us who was very healthy. We did the initial tests and everything looked great. Nobody is perfect. There are always things to tweak, but generally speaking, it was moving in the right direction. We had a plan. We said, “Let’s get some cardiac imaging just to make sure there are no issues there.” We did images of his heart, and we found that there were major blockages.

Nobody has a perfect body. There are always things to tweak.

This was probably something that he’s had his whole life, but it was a major risk that could cause him could basically have a heart attack and die. There was some significant, not an insignificant chance that that would happen, and because we found it, we could address it. That’s something that was like a ticking time bomb that may have had a huge impact. I’ll give you one other example, which is a funny one, but we’ve started to go deep into some of these environmental health things, and we use an air monitor in our house.

We recommend that some patients get some air. I have one in my house, and our doctors have them in their house, and some of our patients have asked about this, and we had one patient who decided to get one of these air monitors, like a couple of hundred bucks called AirThings. She put it up, and turns out that his house had a ton of Boron. He’s been breathing just for years, which has all of these other negative consequences in his life.

He was unaware of, and the testing did our testing didn’t show that he had issues with Boron exposure. That’s not a test that we would normally do, but we found it in the air. He had to get a specialist, as it wasn’t cheap to fix it, but he found one, and he fixed it. These are the kinds of things that something like that is wreaking havoc on your health. You have no idea. If you take the action, maybe it’s $1,000 or $1,500 to fix it or something.

Now it pays dividends for the rest of the time. At least, you’re living in that house. You he didn’t have to sell his house, didn’t have to move. He didn’t have to deal with all of that. He was able to address it. He never would have found it. Those are three. We’ve got tons of examples. Every single person who’s been in our program, we’ve got about a hundred, has had some significant finding or change that then led to significant improvement.

Get In Touch With Jesse, Hunter, And Longevity Health

Thank you so much for sharing that. This is really fascinating. I love the clear framework that you’re bringing to this. You’ve identified these three problems, you’ve created a solution for them, and then you have this framework around that that is really super helpful. Starting with the why, the how, and then the what. A simple way to enable people and equip people to do that. Thank you so much for this. I love the approach that you’re taking. I think it’s going to be extremely beneficial to many people. I know you mentioned before, but where can people find this? Where can they sign up for a free consultation, and how do we get connected and go from there?

LongevityHealth.me. That’s our website. You can sign up for a free consult. I still do all the consults, the first consults initially myself. If you sign up for a free consult, you’ll see me. You can go to the website. You can also follow me on LinkedIn, Jesse Levey. I’m posting most days, a bunch of content. Also on our website, we have a free longevity guide. You can sign up for the longevity guide. It’s a five-part series that will give you the tools to implement this stuff yourself. A lot of the things that we’ve talked about are in the guide with more details on how to do it. You get a newsletter once a week. You can sign up for that as well. You can reach out to me on LinkedIn or Jesse@Longevityhealth.me. That’s my email.

Thank you both so much for using your experience, expertise, wisdom, gifts, and talents to really impact people’s lives and make a significant difference. I just applaud you on the vision to help a billion people live to a hundred healthily. It’s a beautiful vision, and you have a way to actually get there. This is exciting stuff. Thanks to both of you so much.

Thanks for having us.

What a great episode with Jesse and Hunter from Longevity Health. I love the framework that they bring to this. We talked through that with Jesse, thinking about starting with your why. I love how he clarified that so clearly and simply. He wants to ski in his 80s, hike in his 90s, and be alive at 102 to meet his great-grandkids. He has a clear why. From there, you can move into the how.

For him, that’s going to be really focusing on his V02 max and having a plan in place for how he is going to deal with those, the four horsemen, as Peter Attia talks about heart, diabetes, dementia, and cancer. How do we avoid dying from one of those things? For him, it’s really moving from there into the what the, and that’s VO2 max for him. He’s going to do intervals and focus on that.

As you said, that might be different for his wife. He’s focused on bone density and improving her bone density. I’m having that framework in place, but then using these tests to inform that framework and inform that strategy. Really taking this simple yet very strategic approach and so doing this extensive blood work, having a DEXA scan, maybe wearing a continuous glucose monitor or something that can help you with that.

Check out their free longevity guide. You can go to LongevityHealth.me or send Jesse an email there, Jesse@LongevityHealth.me. They do have those three different approaches there, more of the concierge approach. That’s where you get the full longevity board of physicians, exercise physiologists, nutritionalists, and strength coaches all looking at your case.

There’s the AI agent plus doctor empowered kind. In the future, hopefully, we will have an AI agent that will be able to really do this at scale for maybe $10 a month. That’s all coming. It’s super exciting. I just love the vision too. Let’s help a billion people live to a hundred healthily. Thanks for tuning in. We’ll see you back here next time.

 

 

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